Intranasal Immunization with Influenza Virus-Like Particles Containing Membrane-Anchored Cholera Toxin B or Ricin Toxin B Enhances Adaptive Immune Responses and Protection against an Antigenically Distinct Virus

Intranasal Immunization with Influenza Virus-Like Particles Containing Membrane-Anchored Cholera Toxin B or Ricin Toxin B Enhances Adaptive Immune Responses and Protection against an Antigenically Distinct Virus

Vaccination is the most effective means to prevent influenza virus infection, although current approaches are associated with suboptimal efficacy. Here, we generated virus-like particles (VLPs) composed of the hemagglutinin (HA), neuraminidase (NA) and matrix protein (M1) of A/Changchun/01/2009 (H1N...

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Bibliographic Details
Main Authors: Ji, Xianliang, Ren, Zhiguang, Xu, Na, Meng, Lingnan, Yu, Zhijun, Feng, Na, Sang, Xiaoyu, Li, Shengnan, Li, Yuanguo, Wang, Tiecheng, Zhao, Yongkun, Wang, Hualei, Zheng, Xuexing, Jin, Hongli, Li, Nan, Yang, Songtao, Cao, Jinshan, Liu, Wensen, Gao, Yuwei, Xia, Xianzhu
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848608/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848608/

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