Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus

Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus

Diverse pathogenic agents often utilize overlapping host networks, and hub proteins within these networks represent attractive targets for broad-spectrum drugs. Using bacterial toxins, we describe a new approach for discovering broad-spectrum therapies capable of inhibiting host proteins that mediat...

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Bibliographic Details
Main Authors: Leonardi, William, Zilbermintz, Leeor, Cheng, Luisa W., Zozaya, Josue, Tran, Sharon H., Elliott, Jeffrey H., Polukhina, Kseniya, Manasherob, Robert, Li, Amy, Chi, Xiaoli, Gharaibeh, Dima, Kenny, Tara, Zamani, Rouzbeh, Soloveva, Veronica, Haddow, Andrew D., Nasar, Farooq, Bavari, Sina, Bassik, Michael C., Cohen, Stanley N., Levitin, Anastasia, Martchenko, Mikhail
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043268/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043268/

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