The influence of dietary sodium content on the pharmacokinetics and pharmacodynamics of fimasartan
A low sodium diet enhances the hemodynamic effect of renin–angiotensin system blockers. It was suggested that the substrates of P-glycoprotein or cytochrome P450 3A4 were reduced on a high sodium diet. This study aimed to investigate the influence of high sodium diet on the pharmacokinetics and phar...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Dove Medical Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844258/ |