Posttranslational hypusination of the eukaryotic translation initiation factor-5A regulates Fusarium graminearum virulence

Posttranslational hypusination of the eukaryotic translation initiation factor-5A regulates Fusarium graminearum virulence

Activation of eukaryotic translation initiation factor eIF5A requires a posttranslational modification, forming the unique amino acid hypusine. This activation is mediated by two enzymes, deoxyhypusine synthase, DHS, and deoxyhypusine hydroxylase, DOHH. The impact of this enzymatic complex on the li...

Full description

Bibliographic Details
Main Authors:	Martinez-Rocha, Ana Lilia, Woriedh, Mayada, Chemnitz, Jan, Willingmann, Peter, Kröger, Cathrin, Hadeler, Birgit, Hauber, Joachim, Schäfer, Wilhelm
Format:	Online
Language:	English
Published:	Nature Publishing Group 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838825/

Similar Items

Molecular Keys to the Janthinobacterium and Duganella spp. Interaction with the Plant Pathogen Fusarium graminearum
by: Haack, Frederike S., et al.
Published: (2016)

Fusarium graminearum forms mycotoxin producing infection structures on wheat
by: Boenisch, Marike J, et al.
Published: (2011)

Expression of Eukaryotic Initiation Factor 5A and Hypusine Forming Enzymes in Glioblastoma Patient Samples: Implications for New Targeted Therapies
by: Preukschas, Michael, et al.
Published: (2012)

Glycosylphosphatidylinositol-Anchored Proteins in Fusarium graminearum: Inventory, Variability, and Virulence
by: Rittenour, William R., et al.
Published: (2013)

Identification of ABC Transporter Genes of Fusarium graminearum with Roles in Azole Tolerance and/or Virulence
by: Abou Ammar, Ghada, et al.
Published: (2013)

Genome-wide expression profiling shows transcriptional reprogramming in Fusarium graminearum by Fusarium graminearum virus 1-DK21 infection
by: Cho, Won Kyong, et al.
Published: (2012)

The Transcription Cofactor Swi6 of the Fusarium graminearum Is Involved in Fusarium Graminearum Virus 1 Infection-Induced Phenotypic Alterations
by: Son, Moonil, et al.
Published: (2016)

Protein-protein-interaction Network Organization of the Hypusine Modification System*
by: Sievert, Henning, et al.
Published: (2012)

Comparison of Trichothecene Biosynthetic Gene Expression between Fusarium graminearum and Fusarium asiaticum
by: Lee, Theresa, et al.
Published: (2014)

Characterisation of the Fusarium graminearum-Wheat Floral Interaction
by: Brown, Neil A., et al.
Published: (2011)

eFG: an electronic resource for Fusarium graminearum
by: Liu, Xiaoping, et al.
Published: (2013)

A new PCR approach for the identification of Fusarium graminearum
by: de Biazio, Gleison Ricardo, et al.
Published: (2008)

Sexual Development and Ascospore Discharge in Fusarium graminearum
by: Cavinder, Brad, et al.
Published: (2012)

Genome Sequence of Fusarium graminearum Isolate CS3005
by: Gardiner, Donald M., et al.
Published: (2014)

Fusarium graminearum 1H NMR metabolomics
by: A. Sevastos, et al.
Published: (2018-08-01)

Erratum to: Transcriptome analysis of maize resistance to Fusarium graminearum
by: Liu, Yongjie, et al.
Published: (2016)

Systematic analysis of the lysine acetylome in Fusarium graminearum
by: Zhou, Shanyue, et al.
Published: (2016)

Factors Influencing Production of Fusaristatin A in Fusarium graminearum
by: Hegge, Anne, et al.
Published: (2015)

Transcriptome analysis of wheat inoculated with Fusarium graminearum
by: Erayman, Mustafa, et al.
Published: (2015)

Extracellular peptidases of the cereal pathogen Fusarium graminearum
by: Lowe, Rohan G. T., et al.
Published: (2015)

Transcriptome analysis of maize resistance to Fusarium graminearum
by: Liu, Yongjie, et al.
Published: (2016)

The Adenylyl Cyclase Plays a Regulatory Role in the Morphogenetic Switch from Vegetative to Pathogenic Lifestyle of Fusarium graminearum on Wheat
by: Bormann, Jörg, et al.
Published: (2014)

Characterization of a novel polyclonal anti-hypusine antibody
by: Nishiki, Yurika, et al.
Published: (2013)

Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication
by: Olsen, Michelle E., et al.
Published: (2016)

A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in Leishmania donovani
by: Chawla, Bhavna, et al.
Published: (2012)

Involvement of a Velvet Protein FgVeA in the Regulation of Asexual Development, Lipid and Secondary Metabolisms and Virulence in Fusarium graminearum
by: Jiang, Jinhua, et al.
Published: (2011)

Network-Based Data Integration for Selecting Candidate Virulence Associated Proteins in the Cereal Infecting Fungus Fusarium graminearum
by: Lysenko, Artem, et al.
Published: (2013)

The bZIP Transcription Factor Fgap1 Mediates Oxidative Stress Response and Trichothecene Biosynthesis But Not Virulence in Fusarium graminearum
by: Montibus, Mathilde, et al.
Published: (2013)

Functional Roles of FgLaeA in Controlling Secondary Metabolism, Sexual Development, and Virulence in Fusarium graminearum
by: Kim, Hee-Kyoung, et al.
Published: (2013)

Heat shock protein 90 is required for sexual and asexual development, virulence, and heat shock response in Fusarium graminearum
by: Bui, Duc-Cuong, et al.
Published: (2016)

The FgNot3 Subunit of the Ccr4-Not Complex Regulates Vegetative Growth, Sporulation, and Virulence in Fusarium graminearum
by: Bui, Duc-Cuong, et al.
Published: (2016)

Whole-genome analysis of Fusarium graminearum insertional mutants identifies virulence associated genes and unmasks untagged chromosomal deletions
by: Urban, Martin, et al.
Published: (2015)

Functional Analysis of the Kinome of the Wheat Scab Fungus Fusarium graminearum
by: Wang, Chenfang, et al.
Published: (2011)

FGDB: a comprehensive fungal genome resource on the plant pathogen Fusarium graminearum
by: Güldener, Ulrich, et al.
Published: (2006)

Heterochromatin influences the secondary metabolite profile in the plant pathogen Fusarium graminearum
by: Reyes-Dominguez, Yazmid, et al.
Published: (2012)

Analysis of simple sequence repeats (SSRs)dynamics in fungus Fusarium graminearum
by: Singh, Rajender, et al.
Published: (2011)

Control of Glucosylceramide Production and Morphogenesis by the Bar1 Ceramide Synthase in Fusarium graminearum
by: Rittenour, William R., et al.
Published: (2011)

Tri6 Is a Global Transcription Regulator in the Phytopathogen Fusarium graminearum
by: Nasmith, Charles G., et al.
Published: (2011)

Population Structure and Genetic Diversity of the Fusarium graminearum Species Complex
by: Wang, Jian-Hua, et al.
Published: (2011)

Molecular systematics, mating population and mycotoxin production of Fusarium graminearum from grasses.
by: Zakaria, Latiffah
Published: (2015)