Posttranslational hypusination of the eukaryotic translation initiation factor-5A regulates Fusarium graminearum virulence

Posttranslational hypusination of the eukaryotic translation initiation factor-5A regulates Fusarium graminearum virulence

Activation of eukaryotic translation initiation factor eIF5A requires a posttranslational modification, forming the unique amino acid hypusine. This activation is mediated by two enzymes, deoxyhypusine synthase, DHS, and deoxyhypusine hydroxylase, DOHH. The impact of this enzymatic complex on the li...

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Bibliographic Details
Main Authors: Martinez-Rocha, Ana Lilia, Woriedh, Mayada, Chemnitz, Jan, Willingmann, Peter, Kröger, Cathrin, Hadeler, Birgit, Hauber, Joachim, Schäfer, Wilhelm
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838825/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838825/

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