A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals

Large-scale sequencing in the 1000 Genomes Project has revealed multitudes of single nucleotide variants (SNVs). Here, we provide insights into the functional effect of these variants using allele-specific behaviour. This can be assessed for an individual by mapping ChIP-seq and RNA-seq reads to a p...

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Bibliographic Details
Main Authors: Chen, Jieming, Rozowsky, Joel, Galeev, Timur R., Harmanci, Arif, Kitchen, Robert, Bedford, Jason, Abyzov, Alexej, Kong, Yong, Regan, Lynne, Gerstein, Mark
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837449/