MUSIC: identification of enriched regions in ChIP-Seq experiments using a mappability-corrected multiscale signal processing framework
We present MUSIC, a signal processing approach for identification of enriched regions in ChIP-Seq data, available at music.gersteinlab.org. MUSIC first filters the ChIP-Seq read-depth signal for systematic noise from non-uniform mappability, which fragments enriched regions. Then it performs a multi...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234855/ |