Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle

Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle

Limb-girdle muscular dystrophy type 2A (LGMD2A) is a form of muscular dystrophy caused by mutations in calpain 3 (CAPN3). Several studies have implicated Ca2+ dysregulation as an underlying event in several muscular dystrophies, including LGMD2A. In this study we used mouse and human myotube culture...

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Bibliographic Details
Main Authors: Toral-Ojeda, Ivan, Aldanondo, Garazi, Lasa-Elgarresta, Jaione, Lasa-Fernández, Haizpea, Fernández-Torrón, Roberto, López de Munain, Adolfo, Vallejo-Illarramendi, Ainara
Format: Online
Language:English
Published: Cambridge University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836212/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836212/

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