Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods
Mendelian randomization is the use of genetic instrumental variables to obtain causal inferences from observational data. Two recent developments for combining information on multiple uncorrelated instrumental variables (IVs) into a single causal estimate are as follows: (i) allele scores, in which...
| Main Authors: | , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
John Wiley and Sons Inc.
2015
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832315/ |