Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

Genome-wide association studies, which typically report regression coefficients summarizing the associations of many genetic variants with various traits, are potentially a powerful source of data for Mendelian randomization investigations. We demonstrate how such coefficients from multiple variants...

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Bibliographic Details
Main Authors: Burgess, Stephen, Butterworth, Adam, Thompson, Simon G
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377079/