Non-sequential and multi-step splicing of the dystrophin transcript

The dystrophin protein encoding DMD gene is the longest human gene. The 2.2 Mb long human dystrophin transcript takes 16 hours to be transcribed and is co-transcriptionally spliced. It contains long introns (24 over 10kb long, 5 over 100kb long) and the heterogeneity in intron size makes it an ideal...

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Bibliographic Details
Main Authors: Gazzoli, Isabella, Pulyakhina, Irina, Verwey, Nisha E., Ariyurek, Yavuz, Laros, Jeroen F. J., 't Hoen, Peter A. C., Aartsma-Rus, Annemieke
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829307/