Non-sequential and multi-step splicing of the dystrophin transcript
The dystrophin protein encoding DMD gene is the longest human gene. The 2.2 Mb long human dystrophin transcript takes 16 hours to be transcribed and is co-transcriptionally spliced. It contains long introns (24 over 10kb long, 5 over 100kb long) and the heterogeneity in intron size makes it an ideal...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829307/ |