Autophagy is Impaired in the Tibialis Anterior of Dystrophin Null Mice

Background Duchenne muscular dystrophy is a lethal, progressive, muscle-wasting disease caused by mutations in the DMD gene. Structural remodelling processes are responsible for muscle atrophy and replacement of myofibers by fibrotic and adipose tissues. Molecular interventions modulating catabolic...

Full description

Bibliographic Details
Main Authors: Spitali, Pietro, Grumati, Paolo, Hiller, Monika, Chrisam, Martina, Aartsma-Rus, Annemieke, Bonaldo, Paolo
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839594/