Generation of Hprt-disrupted rat through mouse←rat ES chimeras

We established rat embryonic stem (ES) cell lines from a double transgenic rat line which harbours CAG-GFP for ubiquitous expression of GFP in somatic cells and Acr3-EGFP for expression in sperm (green body and green sperm: GBGS rat). By injecting the GBGS rat ES cells into mouse blastocysts and tra...

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Bibliographic Details
Main Authors: Isotani, Ayako, Yamagata, Kazuo, Okabe, Masaru, Ikawa, Masahito
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827079/