Long term Glycemic Control Using Polymer Encapsulated, Human Stem-Cell Derived β-cells in Immune Competent mice

The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control in diabetic patients1. Pancreas transplantation and the infusion of cadaveric islets are currently implemented clinically2, but are limited by the adverse effects of lifetime immuno...

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Bibliographic Details
Main Authors: Vegas, Arturo J., Veiseh, Omid, Gürtler, Mads, Millman, Jeffrey R., Pagliuca, Felicia W., Bader, Andrew R., Doloff, Joshua C., Li, Jie, Chen, Michael, Olejnik, Karsten, Tam, Hok Hei, Jhunjhunwala, Siddharth, Langan, Erin, Aresta-Dasilva, Stephanie, Gandham, Srujan, McGarrigle, James, Bochenek, Matthew A., Hollister-Lock, Jennifer, Oberholzer, Jose, Greiner, Dale L., Weir, Gordon C., Melton, Douglas A., Langer, Robert, Anderson, Daniel G.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825868/