Exosome-associated AAV vector as a robust and convenient neuroscience tool
Adeno-associated virus (AAV) vectors are showing promise in gene therapy trials and have proven to be extremely efficient biological tools in basic neuroscience research. One major limitation to their widespread use in the neuroscience laboratory is the cost, labor, skill, and time intense purificat...
Main Authors: | Hudry, Eloise, Martin, Courtney, Gandhi, Sheetal, György, Bence, Scheffer, Deborah I., Mu, Dakai, Merkel, Steven F., Mingozzi, Federico, Fitzpatrick, Zachary, Dimant, Hemi, Masek, Marissa, Ragan, Tim, Tan, Sisareuth, Brisson, Alain R., Ramirez, Servio H., Hyman, Bradley T., Maguire, Casey A. |
---|---|
Format: | Online |
Language: | English |
Published: |
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824662/ |
Similar Items
-
Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9
by: Dashkoff, Jonathan, et al.
Published: (2016) -
Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions
by: Basner-Tschakarjan, Etiena, et al.
Published: (2014) -
Direct Visualization of CHIP-Mediated Degradation of Alpha-Synuclein In Vivo: Implications for PD Therapeutics
by: Dimant, Hemi, et al.
Published: (2014) -
AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes
by: Hui, Daniel J, et al.
Published: (2015) -
IL12-Mediated Liver Inflammation Reduces the Formation of AAV Transcriptionally Active Forms but Has No Effect over Preexisting AAV Transgene Expression
by: Gil-Fariña, Irene, et al.
Published: (2013)