Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells

Cancer stem cells (CSCs) appear to explain many aspects of the neoplastic evolution of tumors and likely account for enhanced therapeutic resistance following treatment. Dysregulated Notch signaling, which affects CSCs plays an important role in pancreatic cancer progression. We have determined the...

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Bibliographic Details
Main Authors: Ponnurangam, Sivapriya, Dandawate, Prasad R., Dhar, Animesh, Tawfik, Ossama W., Parab, Rajashri R., Mishra, Prabhu Dutt, Ranadive, Prafull, Sharma, Rajiv, Mahajan, Girish, Umar, Shahid, Weir, Scott J., Sugumar, Aravind, Jensen, Roy A., Padhye, Subhash B., Balakrishnan, Arun, Anant, Shrikant, Subramaniam, Dharmalingam
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823101/