Crocetinic acid inhibits hedgehog signaling to inhibit pancreatic cancer stem cells

Pancreatic cancer is the fourth leading cause of cancer deaths in the US and no significant treatment is currently available. Here, we describe the effect of crocetinic acid, which we purified from commercial saffron compound crocetin using high performance liquid chromatography. Crocetinic acid inh...

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Bibliographic Details
Main Authors: Rangarajan, Parthasarathy, Subramaniam, Dharmalingam, Paul, Santanu, Kwatra, Deep, Palaniyandi, Kanagaraj, Islam, Shamima, Harihar, Sitaram, Ramalingam, Satish, Gutheil, William, Putty, Sandeep, Pradhan, Rohan, Padhye, Subhash, Welch, Danny R., Anant, Shrikant, Dhar, Animesh
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695016/