Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos

Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos

The major and essential objective of pre-implantation development is to establish embryonic and extra-embryonic cell fates. To address when and how this fundamental process is initiated in mammals, we characterize transcriptomes of all individual cells throughout mouse pre-implantation development....

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Bibliographic Details
Main Authors: Goolam, Mubeen, Scialdone, Antonio, Graham, Sarah J.L., Macaulay, Iain C., Jedrusik, Agnieszka, Hupalowska, Anna, Voet, Thierry, Marioni, John C., Zernicka-Goetz, Magdalena
Format: Online
Language:English
Published: Cell Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819611/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819611/

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