Identification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism

Identification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism

Pyrrolizidine Alkaloids (PAs) are currently one of the most important botanical hepatotoxic ingredients. Glutathion (GSH) metabolism is the most reported pathway involved in hepatotoxicity mechanism of PAs. We speculate that, for different PAs, there should be a common mechanism underlying their hep...

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Bibliographic Details
Main Authors: Yan, Xinmiao, Kang, Hong, Feng, Jun, Yang, Yiyan, Tang, Kailin, Zhu, Ruixin, Yang, Li, Wang, Zhengtao, Cao, Zhiwei
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813181/

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