A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine
Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Royal Society of Chemistry
2013
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Online Access: | http://eprints.nottingham.ac.uk/35316/ http://eprints.nottingham.ac.uk/35316/ http://eprints.nottingham.ac.uk/35316/ http://eprints.nottingham.ac.uk/35316/1/ChemComm%202013.pdf |