Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility

The signaling events that drive familial breast cancer (FBC) risk remain poorly understood. While the majority of genomic studies have focused on genetic risk variants, known risk variants account for at most 30% of FBC cases. Considering that multiple genes may influence FBC risk, we hypothesized t...

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Bibliographic Details
Main Authors: Piccolo, Stephen R, Hoffman, Laura M, Conner, Thomas, Shrestha, Gajendra, Cohen, Adam L, Marks, Jeffrey R, Neumayer, Leigh A, Agarwal, Cori A, Beckerle, Mary C, Andrulis, Irene L, Spira, Avrum E, Moos, Philip J, Buys, Saundra S, Johnson, William Evan, Bild, Andrea H
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812528/