A genomic approach to predict synergistic combinations for breast cancer treatment

We leverage genomic and biochemical data to identify synergistic drug regimens for breast cancer. In order to study the mechanism of the histone deacetylase (HDAC) inhibitors valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA) in breast cancer, we generated and validated genomic profiles...

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Bibliographic Details
Main Authors: Soldi, Raffaella, Cohen, Adam L, Cheng, Luis, Sun, Ying, Moos, Philip, Bild, Andrea H
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450767/