RBP2 Promotes Adult Acute Lymphoblastic Leukemia by Upregulating BCL2

Despite recent increases in the cure rate of acute lymphoblastic leukemia (ALL), adult ALL remains a high-risk disease that exhibits a high relapse rate. In this study, we found that the histone demethylase retinoblastoma binding protein-2 (RBP2) was overexpressed in both on-going and relapse cases...

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Bibliographic Details
Main Authors: Wang, Xiaoming, Zhou, Minran, Fu, Yue, Sun, Ting, Chen, Jin, Qin, Xuemei, Yu, Yuan, Jia, Jihui, Chen, Chunyan
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805198/