Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort

Clinical features of TBK1 carriers compared with C9orf72, GRN and non-mutation carriers in a Belgian cohort

Loss-of-function mutations in TBK1 have been identified in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Van Mossevelde et al. compare TBK1-mutation carriers with FTD, ALS or FTD-ALS to patients carrying GRN or C9orf72 mutations. Differences are seen in age of onset, extrapy...

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Bibliographic Details
Main Authors: Van Mossevelde, Sara, van der Zee, Julie, Gijselinck, Ilse, Engelborghs, Sebastiaan, Sieben, Anne, Van Langenhove, Tim, De Bleecker, Jan, Baets, Jonathan, Vandenbulcke, Mathieu, Van Laere, Koen, Ceyssens, Sarah, Van den Broeck, Marleen, Peeters, Karin, Mattheijssens, Maria, Cras, Patrick, Vandenberghe, Rik, De Jonghe, Peter, Martin, Jean-Jacques, De Deyn, Peter P., Cruts, Marc, Van Broeckhoven, Christine
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805085/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805085/

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