Novel point mutations in the ERG11 gene in clinical isolates of azole resistant Candida species
The azoles are the class of medications most commonly used to fight infections caused by Candida sp. Typically, resistance can be attributed to mutations in ERG11 gene (CYP51) which encodes the cytochrome P450 14α-demethylase, the primary target for the activity of azoles. The objective of this stud...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Instituto Oswaldo Cruz, Ministério da Saúde
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804502/ |