Structural basis for heterogeneous phenotype of ERG11 dependent Azole resistance in C.albicans clinical isolates
Correlating antifungal Azole drug resistance and mis-sense mutations of ERG11 has been paradoxical in pathogenic yeast Candida albicans. Amino acid substitutions (single or multiple) are frequent on ERG11, a membrane bound enzyme of Ergosterol biosynthesis pathway. Presence or absence of mutations c...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Springer International Publishing
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237678/ |