Structure–activity relationship study of angiotensin II analogs in terms of β‐arrestin‐dependent signaling to aldosterone production

Structure–activity relationship study of angiotensin II analogs in terms of β‐arrestin‐dependent signaling to aldosterone production

The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion induction, a steroid hormone that contributes to the pathology of postmyocardial infarction (MI) heart failure (HF), is mediated by both Gq/11 proteins and β‐arrestins, both of which couple to the AngII type...

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Bibliographic Details
Main Authors: Valero, Thairy Reyes, Sturchler, Emmanuel, Jafferjee, Malika, Rengo, Giuseppe, Magafa, Vassiliki, Cordopatis, Paul, McDonald, Patricia, Koch, Walter J., Lymperopoulos, Anastasios
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804318/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804318/

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