Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison

Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison

The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion is mediated by either Gq/11 proteins or βarrestin1 (βarr1), both of which can couple to its type 1 receptors (AT1Rs), present in adrenocortical zona glomerulosa (AZG) cell membranes. In the present study, we...

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Bibliographic Details
Main Authors: Dabul, Samalia, Bathgate-Siryk, Ashley, Valero, Thairy Reyes, Jafferjee, Malika, Sturchler, Emmanuel, McDonald, Patricia, Koch, Walter J., Lymperopoulos, Anastasios
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309955/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309955/

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