Phorbol ester-induced neutrophilic inflammatory responses selectively promote metastatic spread of melanoma in a TLR4-dependent manner

Increased neutrophil counts both in tumor tissue and peripheral blood correlate with poor clinical outcome in melanoma patients suggesting a pro-tumorigenic role of neutrophils for the pathogenesis of malignant melanoma. Recently, we discovered that neutrophilic skin inflammatory responses induced b...

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Bibliographic Details
Main Authors: Bald, Tobias, Landsberg, Jennifer, Jansen, Philipp, Gaffal, Evelyn, Tüting, Thomas
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801457/

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