Phorbol ester-induced neutrophilic inflammatory responses selectively promote metastatic spread of melanoma in a TLR4-dependent manner
Increased neutrophil counts both in tumor tissue and peripheral blood correlate with poor clinical outcome in melanoma patients suggesting a pro-tumorigenic role of neutrophils for the pathogenesis of malignant melanoma. Recently, we discovered that neutrophilic skin inflammatory responses induced b...
Main Authors: | Bald, Tobias, Landsberg, Jennifer, Jansen, Philipp, Gaffal, Evelyn, Tüting, Thomas |
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Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801457/ |
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