THE TUMOR-PROMOTER PHORBOL ESTER (12-0-TETRADECANOYL-PHORBOL-13-ACETATE), A POTENT AGGREGATING AGENT FOR BLOOD PLATELETS
The phorbol ester 12-0-tetradecanoyl-phorbol-13-acetate, a potent tumor-promoting agent, caused irreversible platelet aggregation when more than 0.02 µM was stirred with human citrated or heparinized platelet-rich plasma (PRP). With washed platelets, 1 nM was effective. The alcohol phorbol, which h...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
1974
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2109156/ |