In cellulo phosphorylation of XRCC4 Ser320 by DNA-PK induced by DNA damage
XRCC4 is a protein associated with DNA Ligase IV, which is thought to join two DNA ends at the final step of DNA double-strand break repair through non-homologous end joining. In response to treatment with ionizing radiation or DNA damaging agents, XRCC4 undergoes DNA-PK-dependent phosphorylation. F...
Main Authors: | , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795952/ |