In cellulo phosphorylation of XRCC4 Ser320 by DNA-PK induced by DNA damage

XRCC4 is a protein associated with DNA Ligase IV, which is thought to join two DNA ends at the final step of DNA double-strand break repair through non-homologous end joining. In response to treatment with ionizing radiation or DNA damaging agents, XRCC4 undergoes DNA-PK-dependent phosphorylation. F...

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Bibliographic Details
Main Authors: Sharma, Mukesh Kumar, Imamichi, Shoji, Fukuchi, Mikoto, Samarth, Ravindra Mahadeo, Tomita, Masanori, Matsumoto, Yoshihisa
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795952/