DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity

DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity

The autoimmune regulator (AIRE) protein is a key mediator of the central tolerance for tissue specific antigens and is involved in transcriptional control of many antigens in thymic medullary epithelial cells (mTEC). Mutations in the AIRE gene cause a rare disease named autoimmune polyendocrinopathy...

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Bibliographic Details
Main Authors: Liiv, Ingrid, Rebane, Ana, Org, Tõnis, Saare, Mario, Maslovskaja, Julia, Kisand, Kai, Juronen, Erkki, Valmu, Leena, Bottomley, Matthew James, Kalkkinen, Nisse, Peterson, Pärt
Format: Online
Language:English
Published: Elsevier Pub. Co 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225445/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225445/

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