Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways

Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways

De novo uridine-diphosphate-N-acetylglucosamine (UDP-GlcNAc) biosynthesis requires glucose, glutamine, acetyl-CoA and uridine, however GlcNAc salvaged from glycoconjugate turnover and dietary sources also makes a significant contribution to the intracellular pool. Herein we ask whether dietary GlcNA...

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Bibliographic Details
Main Authors: Ryczko, Michael C., Pawling, Judy, Chen, Rui, Abdel Rahman, Anas M., Yau, Kevin, Copeland, Julia K., Zhang, Cunjie, Surendra, Anu, Guttman, David S., Figeys, Daniel, Dennis, James W.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789752/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789752/

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