Catch-bond mechanism of the bacterial adhesin FimH

Ligand–receptor interactions that are reinforced by mechanical stress, so-called catch-bonds, play a major role in cell–cell adhesion. They critically contribute to widespread urinary tract infections by pathogenic Escherichia coli strains. These pathogens attach to host epithelia via the adhesin Fi...

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Bibliographic Details
Main Authors: Sauer, Maximilian M., Jakob, Roman P., Eras, Jonathan, Baday, Sefer, Eriş, Deniz, Navarra, Giulio, Bernèche, Simon, Ernst, Beat, Maier, Timm, Glockshuber, Rudi
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786642/