CydDC-mediated reductant export in Escherichia coli controls the transcriptional wiring of energy metabolism and combats nitrosative stress

The CydDC ABC transporter of E. coli exports glutathione and cysteine. Loss of cydDC elicits adaptations in energy metabolism and induces sensitivity to NO. CydDC therefore has a likely role in growth and survival during infection.

Bibliographic Details
Main Authors: Holyoake, Louise V., Hunt, Stuart, Sanguinetti, Guido, Cook, Gregory M., Howard, Mark J., Rowe, Michelle L., Poole, Robert K., Shepherd, Mark
Format: Online
Language:English
Published: Portland Press Ltd. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785604/