Different Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain Astrocytes
Chronic exposure to cadmium (Cd) is known to adversely affect renal function. Our previous studies indicated that Cd induces p53-dependent apoptosis by inhibiting gene expression of the ubiquitin-conjugating enzyme (Ube) 2d family in both human and rat proximal tubular cells. In this study, the effe...
Main Authors: | Lee, Jin-Yong, Tokumoto, Maki, Hattori, Yuta, Fujiwara, Yasuyuki, Shimada, Akinori, Satoh, Masahiko |
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Format: | Online |
Language: | English |
Published: |
Korean Society of Toxicology
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780233/ |
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