Different Regulation of p53 Expression by Cadmium Exposure in Kidney, Liver, Intestine, Vasculature, and Brain Astrocytes

Chronic exposure to cadmium (Cd) is known to adversely affect renal function. Our previous studies indicated that Cd induces p53-dependent apoptosis by inhibiting gene expression of the ubiquitin-conjugating enzyme (Ube) 2d family in both human and rat proximal tubular cells. In this study, the effe...

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Bibliographic Details
Main Authors: Lee, Jin-Yong, Tokumoto, Maki, Hattori, Yuta, Fujiwara, Yasuyuki, Shimada, Akinori, Satoh, Masahiko
Format: Online
Language:English
Published: Korean Society of Toxicology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780233/

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