Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy

The tumor microenvironment has a dynamic and usually cancer-promoting function during all tumorigenic steps. Glioblastoma (GBM) is a fatal tumor of the central nervous system, in which a substantial number of non-tumoral infiltrated cells can be found. Astrocytes neighboring these tumor cells have a...

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Bibliographic Details
Main Authors: Biasoli, D, Sobrinho, M F, da Fonseca, A C C, de Matos, D G, Romão, L, de Moraes Maciel, R, Rehen, S K, Moura-Neto, V, Borges, H L, Lima, F R S
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216902/