The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis

The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis

Oncocytomas are predominantly benign neoplasms possessing pathogenic mitochondrial mutations and accumulation of respiration-defective mitochondria, characteristics of unknown significance. Using exome and transcriptome sequencing, we identified two main subtypes of renal oncocytoma. Type 1 is diplo...

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Bibliographic Details
Main Authors:	Joshi, Shilpy, Tolkunov, Denis, Aviv, Hana, Hakimi, Abraham A., Yao, Ming, Hsieh, James J., Ganesan, Shridar, Chan, Chang S., White, Eileen
Format:	Online
Language:	English
Published:	2015
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779191/

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