Use of bacterial whole-genome sequencing to investigate local persistence and spread in bovine tuberculosis

Use of bacterial whole-genome sequencing to investigate local persistence and spread in bovine tuberculosis

•We performed whole genome sequencing (WGS) of Mycobacterium bovis for a single molecular (VNTR) type.•Under-sampling of one lineage was caused by switching between VNTR-types.•Pairwise SNP distances showed a weak genetic isolation by distance pattern.•Bayesian phylogeographic inference was feasible...

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Bibliographic Details
Main Authors: Trewby, Hannah, Wright, David, Breadon, Eleanor L., Lycett, Samantha J., Mallon, Tom R., McCormick, Carl, Johnson, Paul, Orton, Richard J., Allen, Adrian R., Galbraith, Julie, Herzyk, Pawel, Skuce, Robin A., Biek, Roman, Kao, Rowland R.
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773590/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773590/

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