Regulation of Met1‐linked polyubiquitin signalling by the deubiquitinase OTULIN
Modification of proteins with Met1‐linked ‘linear’ ubiquitin chains has emerged as a key regulatory signal to control inflammatory signalling via the master regulator, the transcription factor nuclear factor κB (NF‐κB). While the assembly machinery, the linear ubiquitin chain assembly complex (LUBAC...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
John Wiley and Sons Inc.
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765238/ |