Structure of the human Parkin ligase domain in an autoinhibited state

by Wauer, Tobias, Komander, David
Published 2013

Ubiquitin modifications

by Swatek, Kirby N, Komander, David
Published 2016

Regulation of Met1‐linked polyubiquitin signalling by the deubiquitinase OTULIN

by Elliott, Paul R., Komander, David
Published 2015

Mechanism of phospho-ubiquitin induced PARKIN activation

by Wauer, Tobias, Simicek, Michal, Schubert, Alexander, Komander, David
Published 2015

Assembly, analysis and architecture of atypical ubiquitin chains

by Hospenthal, Manuela K., Freund, Stefan M.V., Komander, David
Published 2013

Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner

by Bremm, Anja, Moniz, Sonia, Mader, Julia, Rocha, Sonia, Komander, David
Published 2014

Cezanne regulates E2F1-dependent HIF2α expression

by Moniz, Sonia, Bandarra, Daniel, Biddlestone, John, Campbell, Kirsteen J., Komander, David, Bremm, Anja, Rocha, Sonia
Published 2015

Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages

by Min, Mingwei, Mevissen, Tycho E. T., De Luca, Maria, Komander, David, Lindon, Catherine
Published 2015

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

by Kulathu, Yogesh, Garcia, Francisco J., Mevissen, Tycho E.T., Busch, Martin, Arnaudo, Nadia, Carroll, Kate S., Barford, David, Komander, David
Published 2013

The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

by Pruneda, Jonathan N., Durkin, Charlotte H., Geurink, Paul P., Ovaa, Huib, Santhanam, Balaji, Holden, David W., Komander, David
Published 2016

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

by von Muhlinen, Natalia, Akutsu, Masato, Ravenhill, Benjamin J., Foeglein, Ágnes, Bloor, Stuart, Rutherford, Trevor J., Freund, Stefan M.V., Komander, David, Randow, Felix
Published 2012

Ubiquitin chain conformation regulates recognition and activity of interacting proteins

by Ye, Yu, Blaser, Georg, Horrocks, Mathew H., Ruedas-Rama, Maria J., Ibrahim, Shehu, Zhukov, Alexander A., Orte, Angel, Klenerman, David, Jackson, Sophie E., Komander, David
Published 2012

Molecular Basis and Regulation of OTULIN-LUBAC Interaction

by Elliott, Paul R., Nielsen, Sofie V., Marco-Casanova, Paola, Fiil, Berthe Katrine, Keusekotten, Kirstin, Mailand, Niels, Freund, Stefan M.V., Gyrd-Hansen, Mads, Komander, David
Published 2014

Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase*

by Birsa, Nicol, Norkett, Rosalind, Wauer, Tobias, Mevissen, Tycho E. T., Wu, Hsiu-Chuan, Foltynie, Thomas, Bhatia, Kailash, Hirst, Warren D., Komander, David, Plun-Favreau, Helene, Kittler, Josef T.
Published 2014

The tumour suppressor CYLD regulates the p53 DNA damage response

by Fernández-Majada, Vanesa, Welz, Patrick-Simon, Ermolaeva, Maria A., Schell, Michael, Adam, Alexander, Dietlein, Felix, Komander, David, Büttner, Reinhard, Thomas, Roman K., Schumacher, Björn, Pasparakis, Manolis
Published 2016

Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets

by Flierman, Dennis, van der Heden van Noort, Gerbrand J., Ekkebus, Reggy, Geurink, Paul P., Mevissen, Tycho E.T., Hospenthal, Manuela K., Komander, David, Ovaa, Huib
Published 2016

CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling

by Hrdinka, Matous, Fiil, Berthe Katrine, Zucca, Mattia, Leske, Derek, Bagola, Katrin, Yabal, Monica, Elliott, Paul R., Damgaard, Rune Busk, Komander, David, Jost, Philipp J., Gyrd-Hansen, Mads
Published 2016

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis

by Wauer, Tobias, Swatek, Kirby N, Wagstaff, Jane L, Gladkova, Christina, Pruneda, Jonathan N, Michel, Martin A, Gersch, Malte, Johnson, Christopher M, Freund, Stefan MV, Komander, David
Published 2015

Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin

by Michel, Martin A., Elliott, Paul R., Swatek, Kirby N., Simicek, Michal, Pruneda, Jonathan N., Wagstaff, Jane L., Freund, Stefan M.V., Komander, David
Published 2015

On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

by Ekkebus, Reggy, van Kasteren, Sander I., Kulathu, Yogesh, Scholten, Arjen, Berlin, Ilana, Geurink, Paul P., de Jong, Annemieke, Goerdayal, Soenita, Neefjes, Jacques, Heck, Albert J. R., Komander, David, Ovaa, Huib
Published 2013