Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes

Elevated concentrations of albumin in the urine, albuminuria, are a hallmark of diabetic kidney disease and are associated with an increased risk for end-stage renal disease and cardiovascular events. To gain insight into the pathophysiological mechanisms underlying albuminuria, we conducted meta-an...

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Main Authors: Teumer, Alexander, Tin, Adrienne, Sorice, Rossella, Gorski, Mathias, Yeo, Nan Cher, Chu, Audrey Y., Li, Man, Li, Yong, Mijatovic, Vladan, Ko, Yi-An, Taliun, Daniel, Luciani, Alessandro, Chen, Ming-Huei, Yang, Qiong, Foster, Meredith C., Olden, Matthias, Hiraki, Linda T., Tayo, Bamidele O., Fuchsberger, Christian, Dieffenbach, Aida Karina, Shuldiner, Alan R., Smith, Albert V., Zappa, Allison M., Lupo, Antonio, Kollerits, Barbara, Ponte, Belen, Stengel, Bénédicte, Krämer, Bernhard K., Paulweber, Bernhard, Mitchell, Braxton D., Hayward, Caroline, Helmer, Catherine, Meisinger, Christa, Gieger, Christian, Shaffer, Christian M., Müller, Christian, Langenberg, Claudia, Ackermann, Daniel, Siscovick, David, Boerwinkle, Eric, Kronenberg, Florian, Ehret, Georg B., Homuth, Georg, Waeber, Gerard, Navis, Gerjan, Gambaro, Giovanni, Malerba, Giovanni, Eiriksdottir, Gudny, Li, Guo, Wichmann, H. Erich, Grallert, Harald, Wallaschofski, Henri, Völzke, Henry, Brenner, Herrmann, Kramer, Holly, Leach, I. Mateo, Rudan, Igor, Hillege, Hans L., Beckmann, Jacques S., Lambert, Jean Charles, Luan, Jian'an, Zhao, Jing Hua, Chalmers, John, Coresh, Josef, Denny, Joshua C., Butterbach, Katja, Launer, Lenore J., Ferrucci, Luigi, Kedenko, Lyudmyla, Haun, Margot, Metzger, Marie, Woodward, Mark, Hoffman, Matthew J., Nauck, Matthias, Waldenberger, Melanie, Pruijm, Menno, Bochud, Murielle, Rheinberger, Myriam, Verweij, Niek, Wareham, Nicholas J., Endlich, Nicole, Soranzo, Nicole, Polasek, Ozren, van der Harst, Pim, Pramstaller, Peter Paul, Vollenweider, Peter, Wild, Philipp S., Gansevoort, Ron T., Rettig, Rainer, Biffar, Reiner, Carroll, Robert J., Katz, Ronit, Loos, Ruth J.F., Hwang, Shih-Jen, Coassin, Stefan, Bergmann, Sven, Rosas, Sylvia E., Stracke, Sylvia, Harris, Tamara B., Corre, Tanguy, Zeller, Tanja, Illig, Thomas, Aspelund, Thor, Tanaka, Toshiko, Lendeckel, Uwe, Völker, Uwe, Gudnason, Vilmundur, Chouraki, Vincent, Koenig, Wolfgang, Kutalik, Zoltan, O'Connell, Jeffrey R., Parsa, Afshin, Heid, Iris M., Paterson, Andrew D., de Boer, Ian H., Devuyst, Olivier, Lazar, Jozef, Endlich, Karlhans, Susztak, Katalin, Tremblay, Johanne, Hamet, Pavel, Jacob, Howard J., Böger, Carsten A., Fox, Caroline S., Pattaro, Cristian, Köttgen, Anna
Format: Online
Language:English
Published: American Diabetes Association 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764151/