Pharmacogenomics of Anti-platelet Therapy: How much evidence is enough for clinical implementation?

by Perry, Christina G., Shuldiner, Alan R.
Published 2013

Metformin Pharmacogenomics: Current Status and Future Directions

by Pawlyk, Aaron C., Giacomini, Kathleen M., McKeon, Catherine, Shuldiner, Alan R., Florez, Jose C.
Published 2014

Lipoprotein Genotype and Conserved Pathway for Exceptional Longevity in Humans

by Atzmon, Gil, Rincon, Marielisa, Schechter, Clyde B, Shuldiner, Alan R, Lipton, Richard B, Bergman, Aviv, Barzilai, Nir
Published 2006

Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference

by McArdle, Patrick F, Whitcomb, Brian W, Tanner, Keith, Mitchell, Braxton D, Shuldiner, Alan R, Parsa, Afshin
Published 2012

Homozygosity by descent mapping of blood pressure in the Old Order Amish: evidence for sex specific genetic architecture

by McArdle, Patrick F, Dytch, Harvey, O'Connell, Jeffery R, Shuldiner, Alan R, Mitchell, Braxton D, Abney, Mark
Published 2007

Analysis of the bereavement effect after the death of a spouse in the Amish: a population-based retrospective cohort study

by Seifter, Ari, Singh, Sarabdeep, McArdle, Patrick F, Ryan, Kathleen A, Shuldiner, Alan R, Mitchell, Braxton D, Schäffer, Alejandro A
Published 2014

Correlation of Circulating MMP-9 with White Blood Cell Count in Humans: Effect of Smoking

by Snitker, Soren, Xie, Keming, Ryan, Kathleen A., Yu, Daozhan, Shuldiner, Alan R., Mitchell, Braxton D., Gong, Da-Wei
Published 2013

Modeled nitrate levels in well water supplies and prevalence of abnormal thyroid conditions among the Old Order Amish in Pennsylvania

by Aschebrook-Kilfoy, Briseis, Heltshe, Sonya L, Nuckols, John R, Sabra, Mona M, Shuldiner, Alan R, Mitchell, Braxton D, Airola, Matt, Holford, Theodore R, Zhang, Yawei, Ward, Mary H
Published 2012

The C Allele of ATM rs11212617 Does Not Associate With Metformin Response in the Diabetes Prevention Program

by Florez, Jose C., Jablonski, Kathleen A., Taylor, Andrew, Mather, Kieren, Horton, Edward, White, Neil H., Barrett-Connor, Elizabeth, Knowler, William C., Shuldiner, Alan R., Pollin, Toni I.
Published 2012

Comparison of BMI and Physical Activity Between Old Order Amish Children and Non-Amish Children

by Hairston, Kristen G., Ducharme, Julie L., Treuth, Margarita S., Hsueh, Wen-Chi, Jastreboff, Ania M., Ryan, Kathy A., Shi, Xiaolian, Mitchell, Braxton D., Shuldiner, Alan R., Snitker, Soren
Published 2013

Extension of GWAS results for lipid-related phenotypes to extreme obesity using electronic health record (EHR) data and the Metabochip

by Parihar, Ankita, Wood, G. Craig, Chu, Xin, Jin, Qunjan, Argyropoulos, George, Still, Christopher D., Shuldiner, Alan R., Mitchell, Braxton D., Gerhard, Glenn S.
Published 2014

American Diabetes Association and JDRF Research Symposium: Diabetes and the Microbiome

by Semenkovich, Clay F., Danska, Jayne, Darsow, Tamara, Dunne, Jessica L., Huttenhower, Curtis, Insel, Richard A., McElvaine, Allison T., Ratner, Robert E., Shuldiner, Alan R., Blaser, Martin J.
Published 2015

Variable Bone Fragility Associated With an Amish COL1A2 Variant and a Knock-in Mouse Model

by Daley, Ethan, Streeten, Elizabeth A, Sorkin, John D, Kuznetsova, Natalia, Shapses, Sue A, Carleton, Stephanie M, Shuldiner, Alan R, Marini, Joan C, Phillips, Charlotte L, Goldstein, Steven A, Leikin, Sergey, McBride, Daniel J
Published 2010

TCF7L2 Polymorphism, Weight Loss and Proinsulin∶Insulin Ratio in the Diabetes Prevention Program

by McCaffery, Jeanne M., Jablonski, Kathleen A., Franks, Paul W., Dagogo-Jack, Sam, Wing, Rena R., Knowler, William C., Delahanty, Linda, Dabelea, Dana, Hamman, Richard, Shuldiner, Alan R., Florez, Jose C.
Published 2011

Acute-Phase Serum Amyloid A: An Inflammatory Adipokine and Potential Link between Obesity and Its Metabolic Complications

by Yang, Rong-Ze, Lee, Mi-Jeong, Hu, Hong, Pollin, Toni I, Ryan, Alice S, Nicklas, Barbara J, Snitker, Soren, Horenstein, Richard B, Hull, Kristen, Goldberg, Nelson H, Goldberg, Andrew P, Shuldiner, Alan R, Fried, Susan K, Gong, Da-Wei
Published 2006

Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program

by Jablonski, Kathleen A., McAteer, Jarred B., de Bakker, Paul I.W., Franks, Paul W., Pollin, Toni I., Hanson, Robert L., Saxena, Richa, Fowler, Sarah, Shuldiner, Alan R., Knowler, William C., Altshuler, David, Florez, Jose C.
Published 2010

Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program

by Pollin, Toni I., Isakova, Tamara, Jablonski, Kathleen A., de Bakker, Paul I. W., Taylor, Andrew, McAteer, Jarred, Pan, Qing, Horton, Edward S., Delahanty, Linda M., Altshuler, David, Shuldiner, Alan R., Goldberg, Ronald B., Florez, Jose C., Franks, Paul W.
Published 2012

Living the Good Life? Mortality and Hospital Utilization Patterns in the Old Order Amish

by Mitchell, Braxton D., Lee, Woei-Jyh, Tolea, Magdalena I., Shields, Kelsey, Ashktorab, Zahra, Magder, Laurence S., Ryan, Kathleen A., Pollin, Toni I., McArdle, Patrick F., Shuldiner, Alan R., Schäffer, Alejandro A.
Published 2012

Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention Program

by Florez, Jose C., Jablonski, Kathleen A., McAteer, Jarred B., Franks, Paul W., Mason, Clinton C., Mather, Kieren, Horton, Edward, Goldberg, Ronald, Dabelea, Dana, Kahn, Steven E., Arakaki, Richard F., Shuldiner, Alan R., Knowler, William C.
Published 2012

Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed-Pharmacogenomics

by Yerges-Armstrong, Laura M., Ellero-Simatos, Sandrine, Georgiades, Anastasia, Zhu, Hongjie, Lewis, Joshua, Horenstein, Richard B., Beitelshees, Amber L., Dane, Adrie, Reijmers, Theo, Hankemeier, Thomas, Fiehn, Oliver, Shuldiner, Alan R., Kaddurah-Daouk, Rima
Published 2013