Population Structure Shapes Copy Number Variation in Malaria Parasites

Population Structure Shapes Copy Number Variation in Malaria Parasites

If copy number variants (CNVs) are predominantly deleterious, we would expect them to be more efficiently purged from populations with a large effective population size (Ne) than from populations with a small Ne. Malaria parasites (Plasmodium falciparum) provide an excellent organism to examine this...

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Bibliographic Details
Main Authors: Cheeseman, Ian H., Miller, Becky, Tan, John C., Tan, Asako, Nair, Shalini, Nkhoma, Standwell C., De Donato, Marcos, Rodulfo, Hectorina, Dondorp, Arjen, Branch, Oralee H., Mesia, Lastenia Ruiz, Newton, Paul, Mayxay, Mayfong, Amambua-Ngwa, Alfred, Conway, David J., Nosten, François, Ferdig, Michael T., Anderson, Tim J. C.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760083/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760083/

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