pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation

Plasmacytoid dendritic cells (pDCs) exhibit both innate and adaptive functions. In particular they are the main source of type I IFNs and directly impact T cell responses through antigen presentation. We have previously demonstrated that during experimental autoimmune encephalomyelitis (EAE) initiat...

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Bibliographic Details
Main Authors: Duraes, Fernanda V., Lippens, Carla, Steinbach, Karin, Dubrot, Juan, Brighouse, Dale, Bendriss-Vermare, Nathalie, Issazadeh-Navikas, Shohreh, Merkler, Doron, Hugues, Stephanie
Format: Online
Language:English
Published: Academic Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758828/