Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production

Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production

Ribavirin is used as a component of combination therapies for the treatment of chronic hepatitis C virus (HCV) infection together with pegylated interferon and/or direct-acting antiviral drugs. Its mechanism of action, however, is not clear. Direct antiviral activity and immunomodulatory functions h...

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Bibliographic Details
Main Authors: Wang, Yang, McGivern, David R, Cheng, Liang, Li, Guangming, Lemon, Stanley M, Niu, Junqi, Su, Lishan, Reszka-Blanco, Natalia J
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537094/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537094/

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