Drug testing and flow cytometry analysis on a large number of uniform sized tumor spheroids using a microfluidic device

Three-dimensional (3D) tumor spheroid possesses great potential as an in vitro model to improve predictive capacity for pre-clinical drug testing. In this paper, we combine advantages of flow cytometry and microfluidics to perform drug testing and analysis on a large number (5000) of uniform sized t...

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Bibliographic Details
Main Authors: Patra, Bishnubrata, Peng, Chien-Chung, Liao, Wei-Hao, Lee, Chau-Hwang, Tung, Yi-Chung
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753452/