Study of the Chemotactic Response of Multicellular Spheroids in a Microfluidic Device

We report the first application of a microfluidic device to observe chemotactic migration in multicellular spheroids. A microfluidic device was designed comprising a central microchamber and two lateral channels through which reagents can be introduced. Multicellular spheroids were embedded in colla...

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Bibliographic Details
Main Authors: Ayuso, Jose M., Basheer, Haneen A., Monge, Rosa, Sánchez-Álvarez, Pablo, Doblaré, Manuel, Shnyder, Steven D., Vinader, Victoria, Afarinkia, Kamyar, Fernández, Luis J., Ochoa, Ignacio
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596573/