Multipurpose Prevention Approaches with Antiretroviral-Based Formulations
We compared the preclinical safety and efficacy of tenofovir (TFV) 1% gel with that of MZC gel [containing 50 μM MIV-150, 14 mM Zn(O2CCH3)2(H2O)2, and 3% carrageenan] through a series of in vitro, ex vivo, and in vivo assays. The two gels showed good antiviral therapeutic indexes (50% cytotoxic conc...
Main Authors: | Jean-Pierre, Ninochka, Barnable, Patrick, Kizima, Larisa, Rodríguez, Aixa, Seidor, Samantha, Cooney, Michael L., Clark, Meredith R., Doncel, Gustavo F., Robbiani, Melissa, Zydowsky, Thomas M., Teleshova, Natalia, Fernández-Romero, José A. |
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Format: | Online |
Language: | English |
Published: |
American Society for Microbiology
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750675/ |
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