Exposure to MIV-150 from a High-Dose Intravaginal Ring Results in Limited Emergence of Drug Resistance Mutations in SHIV-RT Infected Rhesus Macaques

When microbicides used for HIV prevention contain antiretroviral drugs, there is concern for the potential emergence of drug-resistant HIV following use in infected individuals who are either unaware of their HIV infection status or who are aware but still choose to use the microbicide. Resistant vi...

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Bibliographic Details
Main Authors: Hsu, Mayla, Keele, Brandon F., Aravantinou, Meropi, Krawczyk, Noa, Seidor, Samantha, Abraham, Ciby J., Zhang, Shimin, Rodriguez, Aixa, Kizima, Larisa, Derby, Nina, Jean-Pierre, Ninochka, Mizenina, Olga, Gettie, Agegnehu, Grasperge, Brooke, Blanchard, James, Piatak, Michael J., Lifson, Jeffrey D., Fernández-Romero, José A., Zydowsky, Thomas M., Robbiani, Melissa
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937329/